Líneas de Investigación

  • Neurobiología del Stress y la Resiliencia.
  • Comportamiento y registros electrofisiológicos in vivo
  • Aprendizaje y memoria

Proyectos Vigentes

2016-2019 Proyecto Anillo de Investigación en Ciencia y Tecnología: From presbycusis to dementia: a basic and clinical approach.  Financiado por CONICYT, Proyecto N° ACT-1403, Rol: Investigador Responsable

2014-2017 Proyecto FONDECYT Regular: Effects of n-3 fatty acids and endocannabinoids on learning and auditory attention of chronically stressed rats. Financiado por FONDECYT, Proyecto N° 114-1276, Rol: Investigador Responsable

2013-2016 Proyecto FONDECYT Regular: Regulation of long-term plasticity at inhibitory circuits by acetylcholine: new role of parvalbumin-positive interneurons in the hippocampal function and memory. Financiado por FONDECYT, Proyecto N° 113-0614, Rol: Co-Investigador

Publicaciones

Cannabinoid receptor type 1 modulates the effects of polyunsaturated fatty acids on memory of stressed rats. Peñaloza-Sancho V, Pérez-Valenzuela C, Gonzalez C, Jujihara G, Bustos P, Dagnino-Subiabre A. Nutr Neurosci. 2019 Oct 22:1-18. doi: 10.1080/1028415X.2019.1659561. [Epub ahead of print]

Stress and Western diets increase vulnerability to neuropsychiatric disorders: A common mechanism. Dagnino-Subiabre A. Nutr Neurosci. 2019 Sep 16:1-11. doi: 10.1080/1028415X.2019.1661651. [Epub ahead of print]

Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats. Pérez MÁ, Morales C, Santander O, García F, Gómez I, Peñaloza-Sancho V, Fuentealba P, Dagnino-Subiabre A, Moya PR, Fuenzalida M. Front Cell Neurosci. 2019 Aug 20;13:372. doi: 10.3389/fncel.2019.00372. eCollection 2019.

Impact of Stress on Gamma Oscillations in the Rat Nucleus Accumbens During Spontaneous Social Interaction. Iturra-Mena AM, Aguilar-Rivera M, Arriagada-Solimano M, Pérez-Valenzuela C, Fuentealba P, Dagnino-Subiabre A. Front Behav Neurosci. 2019 Jul 10;13:151. doi: 10.3389/fnbeh.2019.00151. eCollection 2019.

Effects of stress on the auditory system: an approach to study a common origin for mood disorders and dementia. Pérez-Valenzuela C, Terreros G, Dagnino-Subiabre A. Rev Neurosci. 2019 Apr 24;30(3):317-324. doi: 10.1515/revneuro-2018-0018. Review.

Effects of prenatal stress on anxiety- and depressive-like behaviours are sex-specific in prepubertal rats. Iturra-Mena AM, Arriagada-Solimano M, Luttecke-Anders A, Dagnino-Subiabre A. J Neuroendocrinol. 2018 Jul;30(7):e12609. doi: 10.1111/jne.12609.

Difference in Perseverative Errors during a Visual Attention Task with Auditory Distractors in Alpha-9 Nicotinic Receptor Subunit Wild Type and Knock-Out Mice. Jorratt P, Delano PH, Delgado C, Dagnino-Subiabre A, Terreros G. Front Cell Neurosci. 2017 Nov 8;11:357. doi: 10.3389/fncel.2017.00357. eCollection 2017.

Music Training and Education Slow the Deterioration of Music Perception Produced by Presbycusis in the Elderly. Moreno-Gómez FN, Véliz G, Rojas M, Martínez C, Olmedo R, Panussis F, Dagnino-Subiabre A, Delgado C, Delano PH. Front Aging Neurosci. 2017 May 19;9:149. doi: 10.3389/fnagi.2017.00149. eCollection 2017.

n-3 Polyunsaturated fatty acid supplementation restored impaired memory and GABAergic synaptic efficacy in the hippocampus of stressed rats. Pérez MÁ, Peñaloza-Sancho V, Ahumada J, Fuenzalida M, Dagnino-Subiabre A. Nutr Neurosci. 2018 Oct;21(8):556-569. doi: 10.1080/1028415X.2017.1323609. Epub 2017 May 8.

Reboxetine Improves Auditory Attention and Increases Norepinephrine Levels in the Auditory Cortex of Chronically Stressed Rats. Pérez-Valenzuela C, Gárate-Pérez MF, Sotomayor-Zárate R, Delano PH, Dagnino-Subiabre A. Front Neural Circuits. 2016 Dec 27;10:108. doi: 10.3389/fncir.2016.00108. eCollection 2016.

Synaptic Impairment in Layer 1 of the Prefrontal Cortex Induced by Repeated Stress During Adolescence is Reversed in Adulthood. Negrón-Oyarzo I, Dagnino-Subiabre A, Muñoz Carvajal P. Front Cell Neurosci. 2015 Nov 12;9:442. doi: 10.3389/fncel.2015.00442. eCollection 2015.